Archive for November, 2009

FDA warning on negative pressure wound therapy

Monday, November 30th, 2009

Negative pressure (wound vac) therapy was heavily promoted when the technology came out several years ago. It’s easy to use and has become very popular. Now we have this warning from the FDA (via Medscape):

Negative pressure wound therapy (NPWT) systems have been associated with 6 deaths and 77 serious complications during the past 2 years, the US Food and Drug Administration (FDA) has announced.

…The FDA points out that NPWT systems are contraindicated for certain wound types (necrotic tissue with eschar present; untreated osteomyelitis; nonenteric and unexplored fistulas; malignancy in the wound; and wounds with exposed vasculature, nerves, anastomotic site, or organs). Several patient risk factors, including being at high risk for bleeding, should be considered before using NPWT.

My guess (and it’s only a guess) is that, given the promotion, convenience and ease of use, these devices have been widely employed without proper expertise or attention to evidence.

FDA warning on negative pressure wound therapy

Monday, November 30th, 2009

Negative pressure (wound vac) therapy was heavily promoted when the technology came out several years ago. It’s easy to use and has become very popular. Now we have this warning from the FDA (via Medscape):

Negative pressure wound therapy (NPWT) systems have been associated with 6 deaths and 77 serious complications during the past 2 years, the US Food and Drug Administration (FDA) has announced.

…The FDA points out that NPWT systems are contraindicated for certain wound types (necrotic tissue with eschar present; untreated osteomyelitis; nonenteric and unexplored fistulas; malignancy in the wound; and wounds with exposed vasculature, nerves, anastomotic site, or organs). Several patient risk factors, including being at high risk for bleeding, should be considered before using NPWT.

My guess (and it’s only a guess) is that, given the promotion, convenience and ease of use, these devices have been widely employed without proper expertise or attention to evidence.

For All My Startup Founders Workin’ it Out on a Sunday…

Monday, November 30th, 2009

Listening to this on the Blip.FM ContagionHealth channel while working on getupandmove.me UserVoice stuff.

Bang bang bang bang, vamanos, vamanos…

Posted via web from Jen’s Posterous

Kidney International – Table of Contents alert Volume 76 Supplement 114s

Monday, November 30th, 2009

KIDNEY INTERNATIONAL

December 2009 Volume 76 Number S114, pp S1 – S42

International Society of Nephrology
===================================
Your contribution is essential:
Renew your ISN membership now!
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———————-
INTRODUCTION
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Beyond phosphate binding: the effect of binder therapy on novel biomarkers may have clinical implications for the management of chronic kidney disease patients
Gary E Striker
http://links.ealert.nature.com/ctt?kn=9&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

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REVIEWS
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Role of oxidants/inflammation in declining renal function in chronic kidney disease and normal aging
Helen Vlassara, Massimo Torreggiani, James B Post, Feng Zheng, Jaime Uribarri and Gary E Striker
Abstract: http://links.ealert.nature.com/ctt?kn=7&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=6&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

Uremic toxins originating from colonic microbial metabolism
Pieter Evenepoel, Bjorn K I Meijers, Bert R M Bammens and Kristin Verbeke
Abstract: http://links.ealert.nature.com/ctt?kn=44&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=42&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

Endotoxin-binding affinity of sevelamer: a potential novel anti-inflammatory mechanism
Phyllis P Sun, Mary C Perianayagam and Bertrand L Jaber
Abstract: http://links.ealert.nature.com/ctt?kn=46&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=45&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

Sevelamer and the bone-vascular axis in chronic kidney disease: bone turnover, inflammation, and calcification regulation
Vincent M Brandenburg, Willi Jahnen-Dechent and Markus Ketteler
Abstract: http://links.ealert.nature.com/ctt?kn=36&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=37&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

Clinical relevance of FGF-23 in chronic kidney disease
Sarah Seiler, Gunnar H Heine and Danilo Fliser
Abstract: http://links.ealert.nature.com/ctt?kn=38&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=39&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

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Foodbuzz 24 24 24: Giving Thanks

Monday, November 30th, 2009

Happy Thanksgiving everyone!! I hope you all had wonderful days filled with family/friends and good food! I know I am so very thankful to have a loving family, a job, a warm place to sleep, and so many good things to eat. I think it’s easy to take simple pleasures like cooking and eating for granted. It was this inspiration that lead me to this month’s 24 24 24 proposal. I proposed a giving of a

Foodbuzz 24 24 24: Giving Thanks

Monday, November 30th, 2009

Happy Thanksgiving everyone!! I hope you all had wonderful days filled with family/friends and good food! I know I am so very thankful to have a loving family, a job, a warm place to sleep, and so many good things to eat. I think it’s easy to take simple pleasures like cooking and eating for granted. It was this inspiration that lead me to this month’s 24 24 24 proposal. I proposed a giving of a

Ohmmmmm

Monday, November 30th, 2009

So Stoneyfield Oikos yogurt asked us foodbloggers what makes us say ohmmm for a chance to win a crazy spa vacation (it’s a Na-Moo-Ste Giveaway.. HA). Of course I want to win and need to enter!!How to enter…A) Share an original story about why you need to say “Ohm”B) Post a photo of you doing yoga in a toga (Oikos is Greek yogurt after all!)C) Share a recipe you created using Oikos

Ohmmmmm

Monday, November 30th, 2009

So Stoneyfield Oikos yogurt asked us foodbloggers what makes us say ohmmm for a chance to win a crazy spa vacation (it’s a Na-Moo-Ste Giveaway.. HA). Of course I want to win and need to enter!!How to enter…A) Share an original story about why you need to say “Ohm”B) Post a photo of you doing yoga in a toga (Oikos is Greek yogurt after all!)C) Share a recipe you created using Oikos

Twitter and Facebook no longer free?

Monday, November 30th, 2009

Or so it’s rumored.

Twitter and Facebook no longer free?

Monday, November 30th, 2009

Or so it’s rumored.