Archive for October, 2009

Talking Turkey with Prof Trim

Saturday, October 31st, 2009

Why not the Australian Aboriginal diet for health and weight loss?
The Mediterranean diet; a mixture of fruit, nuts, vegetables, seafood, pasta and olive oil has been sold so much as the healthy diet by nutritionists and the medical profession in recent years, that many people think they have to move to Crete or Italy to survive. But as usual, the Professor is here to throw a spanner into the works.

Not only does the real Mediterranean diet hardly still exist in the Mediterranean in its real form, but it’s probably no more healthy than the traditional Aboriginal diet, the Nordic diet, the Hunza diet, the Okinawa diet – or any of a number of other forms of ‘native’ diet eaten traditionally by inhabitants of a particular region before the advent of industrialisation of foods, domestication of animals and proliferation of ‘fast’ foods.

People (including scientists) get carried away with specific diets and components of diets, which they consider to be the elixir for good health, based on the fact that they have been eaten for thousands of years. But humans have existed in all parts of the world for thousands of years and have eaten a wide variety of localized foods. Hence, it’s the common ingredients of such ‘native’ foods that are likely to have the positive benefits, rather than the particular foods themselves. For example, it’s known that native Australian fruits and vegetables are high in anti-oxidants, and the native fish and animal meats are lean and extremely low fat (i.e. healthy).

Recently, your own humble Professor has been involved in a study comparing inflammation markers in the bloodstream of a number of people after a meal of kangaroo (a ‘native’ food), compared to a meal of wagyu beef (a domesticated animal food). Wagyu was only bred into existence about two decades ago. It is reasonably high in fat (although not as bad as some other meat breeds on the market). Kangaroo, on the other hand, has been around for eons, and is very low in fat (in fact hardly any). In the Australian study (yet to be published), kangaroo didn’t increase inflammation, whereas wagyu did.

So why bother with the Mediterranean diet, when here in Australia we have possibly one of the world’s healthiest diets on our doorstep. Although it’s not likely to exist, except in trendy middle class restaurants these days, here is a sample of what you might have expected in the traditional Australian Aboriginal diet:

Land food Water food Sky food
Kangaroo (now marketed as ‘Kroo’), wallaby, emu, goanna, snakes and grubs Fish, crayfish/yabbies, lobster, prawns/shrimp, crabs, octopus, squid Duck, goose, native pigeon, mutton bird, swamp fowl, pheasant
Natives berries and fruits, native vegetables, yams and seeds Water plants Bats

Quandong roo

Photo: Kangaroo fillet with quandong confit courtesy Dining Downunder Promotions chefs Benjamin Christie and Vic Cherikoff

For more information on weight loss for men, check out Professor Trim’s website HERE.

Want to find out more about Australia’s wild foods?
Check out a copy of Vic Cherikoff’s Super Foods for Super Health (with George Kowalski) and read all about Kakadu plum (the world’s highest fruit source of vitamin C), wild rosella, Illawarra plum, mountain pepper, quandong and Australian native herb extracts. If you are inspired to try these wild foods, you won’t find them in your fruit shop – they aren’t available in commercial quantities. ‘Kakadu Juice which is packed with anti-oxidants is the only way we can easily add these wild foods to our diet,’ says Vic.

FDA Says Yes to IV Peramivir To Treat Flu

Saturday, October 31st, 2009

The FDA announced today that it has issued an emergency use authorization (EUA) for the investigational antiviral drug peramivir intravenous (IV) in certain adult and pediatric patients with confirmed or suspected 2009 H1N1 influenza infection who are admitted to a hospital.

Specifically, IV peramivir is authorized only for hospitalized adult and pediatric patients for whom therapy with an IV drug is clinically appropriate, based on one or more of the following reasons:

  • the patient is not responding to either oral or inhaled antiviral therapy, or
  • when drug delivery by a route other than an intravenous route — e.g., enteral (absorbed by the intestines) or inhaled — is not expected to be dependable or feasible;
  • for adults only, when the clinician judges IV therapy is appropriate due to other circumstances.

I’ve been following this drug for sometime now, and I’m glad to see that it’s found a niche during this flu pandemic.

Additional Related Information From The FDA:
EUA Letter of Authorization
EUA Fact Sheet for Health Care Providers
EUA Fact Sheet for Patients and Parents/Caregivers
Information for Healthcare Professionals Sheet (HCP) on mandatory adverse event reporting for emergency use of peramivir under EUA

Previous Posts:
FDA Search Widget of Fraudulent H1N1 Products
Got Wine Flu?
Flu.gov Updated by HHS – New Resources Added

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Scary Things Might Get You

Saturday, October 31st, 2009

ISCO Chairman and CEO Kenneth Aldrich to speak at Stem Cells USA Regenerative Medicine Congress on November

Saturday, October 31st, 2009
Release #:1468-71368-em-434148:

ISCO Chairman and CEO Kenneth Aldrich to speak at Stem Cells USA Regenerative Medicine Congress on November 18, 2009




conference details

Conference:
Day 1
Nov 17, 8:30am – 5:30pm
Day 2
Nov 18, 8:30am – 5:30pm

 
Pre-conference workshop:
Nov 16, 9am – 4:30pm

› Register now and save 15%
› Add this to my calendar

or call +1 212 379 6320

our speakers

Dr Anthony Atala

Director
Wake Forest Institute for Regenerative Medicine

Dr Story Landis

Head of the Stem Cell Task Force
National Institute of Health

Dr Ruth McKernan

Chief Scientific Officer
Pfizer

Mr Paul Grayson

President & CEO
Fate Therapeutics

Dr Yukio Hasegawa
President & CEO
CellSeed

 

Dear Colleague,

Kenneth Aldrich, Chairman and Chief Executive Officer of International Stem Cell Corporation (ISCO.OB) is speaking at Stem Cells USA & Regenerative Medicine Congress on the topic of “Is there a correct business model for regenerative medicine?” and is pleased to extend a 15% discount on your registration.

> Register now and save 15%

Key topics include: 

  • Funding and partnership models
  • Stem cells as tools in predicting drug toxicity
  • Stems cells as tools in drug discovery – target identification and validation
  • Novel strategies for study of disease
  • Commercialization challenges
  • Regulatory updates & strategies to overcome regulatory hurdles
  • Enhanced production & manufacturing systems
  • Big pharma perspective on future commercialization of stem cell therapeutics
  • The challenge of commercialization
  • Cardiovascular stem cell therapeutics
  • Skin, bone and hair stem cell therapeutics

Download the brochure

Be among the following already registered to attend:

Biotec GmbH; WuXi AppTec, Inc; Healthpoint, Ltd.; University of Nebraska Medical Center; Lonza Walkersville; LifeCell Corporation; Sartorius Stedim Biotech; Baxter Healthcare Corporation; Roche; Biomade; ECBio Sa; Medeia Therapeutics Ltd; ECBio Sa; Manufacturing Technology; BD Technologies; Miltenyi Biotec GmbH; Aastrom Biosciences; BD; NFCR; Mars Innovation; Pfizer; Tarix Pathfinder  Pharmaceuticals; Vitrolife Sweden AB; AstraZeneca R&D; University of Minnesota;
American Type Culture Collection; Advenced Technologies & Regenerative Medicine LLC; Invetech, Inc; Medrad, Inc; Cytograft;Theregen;GliaMed,Inc.; Roche; Txcell; BioTime;Stem Cell Therapeutics Corp.; Centocor;Cellerant Therapeutics; Genzyme; Darpha; Safeguard Scientifics; Wake Forest Institute for Regenerative Medicine; Novitas Capital; Baxter; Bay City Capital; Fate Therapeutics;Cell Seed;Proteus Venture Partners; TVM Capital; Organogenesis; The Havard Stem Cell Institute; National Institute of Health; CONNECT; Bioengineering Institute;Stratatech Corporation; Angioblast; Pfizer;Harvard Stem Cell Institute; Cellerix; Merck Research Laboratories; Athersys, Inc.; Advanced BioHealing; Tengion; Food and Drug Administration Center for Biologics Evaluation and Research; Juventas Therapeutics Inc.; Harvard Medical School; Haecker Consulating; University of Pittsburgh School of Medicine; International Stem Cell Corporation (ISCO.OB);Pervasis Therapeutics; GliaMed, Inc.; Novocell; California Stem Cell; University of Minho; Garnet BioTherapeutics; Athersys, Inc.; Drexel University College of Medicine; Advanced BioHealing; Johnson & Johnson; Panacea Biotec Limited and more!

> Learn more about the event

Will you be there to do business and strategize with senior level executives from the leading pharma, biotechs and government organizations?

> Register now and start networking!

 or call +1 212 379 6320

Your voucher code is: KA

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Hospitalists at your beck and call

Friday, October 30th, 2009

New Advances in Applied Mircobiology Volume

Friday, October 30th, 2009
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Advances in Applied Microbiology, Volume 69 
Edited by Allen I. Laskin, Geoffrey M. Gadd, and Sima Sariaslani

TABLE OF CONENTS:

Variation in Form and Function: The Helix-Turn-Helix Regulators of the GntR Superfamily

Biogenesis of the Cell Wall and Other Glycoconjugates of Mycobacterium tuberculosis

Antimicrobial Properties of Hydroxyxanthenes

In Vitro Biofilm Models: An Overview

Zones of Inhibition? The Transfer of Information Relating to Penicillin in Europe during World War II

The Genomes of Lager Yeasts

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New Advances in Genetics Volume

Friday, October 30th, 2009
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Advances in Genetics, Volume 66

Edited by Theodore Friedmann,
Jay C. Dunlap, Stephen F. Goodwin 

Contents include:

The Molecular Links Between TDP-43 Dysfunction and Neurodegeneration
Emanuele Buratti, Francisco E. Baralle

Resources and Strategies to Integrate the Study of Ethical, Legal, and Social Implications of Genetics into the Undergraduate Curriculum
Jinnie M. Garrett, Kathleen L. Triman

Synthetic Genetic Interactions: Allele Dependence, Uses, and Conservation
Joseph V. Gray, Sue A. Krause

 

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Pumpkins Inc.

Friday, October 30th, 2009

If Food Inc. scared you off meat wait till you see today’s Funny Friday video – you may never carve a pumpkin again!

Have a great weekend and Happy Halloween!

(Remember, email subscribers you’ve got to visit the blog to watch)

Pumpkins Inc.

Friday, October 30th, 2009

If Food Inc. scared you off meat wait till you see today’s Funny Friday video – you may never carve a pumpkin again!

Have a great weekend and Happy Halloween!

(Remember, email subscribers you’ve got to visit the blog to watch)

Hospitalists and comanagement—the debate continues

Thursday, October 29th, 2009

But the debate, as illustrated by a point-counterpoint piece in the October issue of The Hospitalist, is not about whether collaboration among hospitalists, surgeons and subspecialists is good for patient care. It’s about the importance of dealing with unintended consequences and defining the relationships.

There are strong arguments in favor of comanagement as a model which benefits patients. It it’s not done carefully, though, the adverse consequences for patient care are many and it is a driver of career dissatisfaction. Eric Siegal, M.D., a co-author of the piece, described a situation all too familiar:

In the wee hours of a recent busy call night, the ED called me to admit a patient whose automatic implantable cardioverter cefibrillator (AICD) had fired repeatedly. The patient had no other active medical issues. When called, the electrophysiologist, who was on staff, demanded that I admit the patient for “medical comanagement.” The specialist agreed that I probably would have little to add to the care, but his firm expectation was that hospitalists admit his patients and he “consults” … especially at 2 a.m.